[HTML][HTML] The human antibacterial cathelicidin, hCAP-18, is bound to lipoproteins in plasma
O Sørensen, T Bratt, AH Johnsen, MT Madsen… - Journal of Biological …, 1999 - ASBMB
Cathelicidins are a family of antibacterial and lipopolysaccharide-binding proteins. hCAP-
18, the only human cathelicidin, is a major protein of the specific granules of human
neutrophils. The plasma level of hCAP-18 is> 20-fold higher than that of other specific
granule proteins relative to their levels within circulating neutrophils. The aim of this study
was to elucidate the background for this high plasma level of hCAP-18. Plasma was
subjected to molecular sieve chromatography, and hCAP-18 was found in distinct high …
18, the only human cathelicidin, is a major protein of the specific granules of human
neutrophils. The plasma level of hCAP-18 is> 20-fold higher than that of other specific
granule proteins relative to their levels within circulating neutrophils. The aim of this study
was to elucidate the background for this high plasma level of hCAP-18. Plasma was
subjected to molecular sieve chromatography, and hCAP-18 was found in distinct high …