[HTML][HTML] Structural requirements of heparan sulfate for the binding to the tumor-derived adhesion factor/angiomodulin that induces cord-like structures to ECV-304 …
J Kishibe, S Yamada, Y Okada, J Sato, A Ito… - Journal of Biological …, 2000 - ASBMB
Tumor-derived adhesion factor/angiomodulin (AGM) is accumulated in tumor blood vessels
and on the endothelial cell surface (Akaogi, K., Okabe, Y., Sato, J., Nagashima, Y.,
Yasumitsu, H., Sugahara, K., and Miyazaki, K.(1996) Proc. Natl. Acad. Sci. USA 93, 8384–
8389). In cell culture, it promotes cell adhesion and morphological changes to form cord-like
structures of the human bladder carcinoma cell line ECV-304. The cord formation is
prevented by heparin, which inhibits the binding of AGM to ECV-304 cells. This observation …
and on the endothelial cell surface (Akaogi, K., Okabe, Y., Sato, J., Nagashima, Y.,
Yasumitsu, H., Sugahara, K., and Miyazaki, K.(1996) Proc. Natl. Acad. Sci. USA 93, 8384–
8389). In cell culture, it promotes cell adhesion and morphological changes to form cord-like
structures of the human bladder carcinoma cell line ECV-304. The cord formation is
prevented by heparin, which inhibits the binding of AGM to ECV-304 cells. This observation …
