A panel of lung injury biomarkers enhances the definition of primary graft dysfunction (PGD) after lung transplantation
RJ Shah, SL Bellamy, AR Localio… - The Journal of heart and …, 2012 - Elsevier
BACKGROUND: We aimed to identify combinations of biomarkers to enhance the definition
of primary graft dysfunction (PGD) for translational research. METHODS: Biomarkers
reflecting lung epithelial injury (soluble receptor for advance glycation end products [sRAGE]
and surfactant protein-D [SP-D]), coagulation cascade (plasminogen activator inhibitor-1
[PAI-1] and protein C), and cell adhesion (intracellular adhesion molecule-1 [ICAM-1]) were
measured in the plasma of 315 individuals derived from the Lung Transplant Outcomes …
of primary graft dysfunction (PGD) for translational research. METHODS: Biomarkers
reflecting lung epithelial injury (soluble receptor for advance glycation end products [sRAGE]
and surfactant protein-D [SP-D]), coagulation cascade (plasminogen activator inhibitor-1
[PAI-1] and protein C), and cell adhesion (intracellular adhesion molecule-1 [ICAM-1]) were
measured in the plasma of 315 individuals derived from the Lung Transplant Outcomes …