Impact of primary graft failure on outcomes following lung transplantation

JD Christie, JS Sager, SE Kimmel, VN Ahya… - Chest, 2005 - Elsevier
Study objectives Primary graft failure (PGF) is a severe acute lung injury syndrome that
occurs following lung transplantation. We compared the clinical outcomes of patients who
developed PGF with those who did not. Methods We conducted a retrospective cohort study
including 255 consecutive lung transplant procedures. PGF was defined as (1) diffuse
alveolar opacities developing within 72 h of transplantation,(2) an arterial partial pressure of
oxygen/fraction of inspired oxygen (Pa o 2/F io 2) ratio of< 200 beyond 48 h postoperatively …