Primary graft dysfunction
JC Lee, JD Christie - Clinics in chest medicine, 2011 - chestmed.theclinics.com
Primary graft dysfunction (PGD), a form of acute lung injury analogous to acute respiratory
distress syndrome (ARDS), arises within the first 72 hours following lung transplantation,
and is a leading cause of early morbidity and mortality. Previously known as “primary graft
failure” or “reperfusion edema,” PGD affects up to 25% of all lung transplant procedures and
currently has no proven preventive therapy. 1–7 When compared with lung transplant
recipients who do not develop PGD, 30-day mortality rates are up to eightfold higher in …
distress syndrome (ARDS), arises within the first 72 hours following lung transplantation,
and is a leading cause of early morbidity and mortality. Previously known as “primary graft
failure” or “reperfusion edema,” PGD affects up to 25% of all lung transplant procedures and
currently has no proven preventive therapy. 1–7 When compared with lung transplant
recipients who do not develop PGD, 30-day mortality rates are up to eightfold higher in …