[HTML][HTML] The role of a low erythropoietin level for the polycythemia vera diagnosis

O Lupak, X Han, P Xie, S Mahmood… - Blood Cells, Molecules …, 2020 - Elsevier
A low erythropoietin (EPO) level is a minor diagnostic criterion for polycythemia vera (PV).
Controversies exist regarding the diagnostic value of a low EPO level when considering
increasing availability of advanced molecular testing. We assessed the role of low EPO level
for PV diagnosis in the context of positive JAK2 mutation status as well as other diagnostic
parameters. Of 138 patients, 75 patients had PV and 63 had secondary erythrocytosis. Of the
75 patients with PV, 32% had EPO levels within the normal range. EPO level positively …