Donor–recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell …
KL McQueen, KM Dorighi, LA Guethlein, R Wong… - Human immunology, 2007 - Elsevier
The influence of donor and recipient killer immunoglobulin-like receptor (KIR) genotype on
the outcome of hematopoietic cell transplantation between human leukocyte antigen (HLA)–
matched siblings was investigated. Transplants were divided into four groups according to
the combination of group A and B KIR haplotypes in the transplant donor and recipient.
Overall survival of myeloid patients varied with KIR genotype combination. Best survival was
associated with the donor lacking and the recipient having group B KIR haplotypes; poorest …
the outcome of hematopoietic cell transplantation between human leukocyte antigen (HLA)–
matched siblings was investigated. Transplants were divided into four groups according to
the combination of group A and B KIR haplotypes in the transplant donor and recipient.
Overall survival of myeloid patients varied with KIR genotype combination. Best survival was
associated with the donor lacking and the recipient having group B KIR haplotypes; poorest …