Studies on the effect of 4-methyl-umbelliferon (Hymecromone) in patients following surgical revision of the biliary pathways

P Walter, W Seidel - Der Chirurg; Zeitschrift fur Alle Gebiete der …, 1979 - europepmc.org
P Walter, W Seidel
Der Chirurg; Zeitschrift fur Alle Gebiete der Operativen Medizen, 1979europepmc.org
The effect of 4-methylumbelliferone (hymecromone) on postoperative gall volume and
residual pressure, serum enzymes, and other parameters in 50 patients after
cholecystectomy and choledochotomy with T-tube drainage is measured by a clinical double-
blind study. There were several interesting findings:(a) significant less gall flowing from the T
tube,(b) highly significant less activity of the enzymes basic phosphatase and of the gamma-
glutamyltranspeptidase, and (c) fewer need of analgesics.
The effect of 4-methylumbelliferone (hymecromone) on postoperative gall volume and residual pressure, serum enzymes, and other parameters in 50 patients after cholecystectomy and choledochotomy with T-tube drainage is measured by a clinical double-blind study. There were several interesting findings:(a) significant less gall flowing from the T tube,(b) highly significant less activity of the enzymes basic phosphatase and of the gamma-glutamyltranspeptidase, and (c) fewer need of analgesics.
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