[HTML][HTML] Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system
IY Mattisson, C Christoffersen - Atherosclerosis, 2021 - Elsevier
Apolipoprotein M (apoM) is a member of the lipocalin superfamily and is predominantly
associated with high-density lipoprotein (HDL). It was found that apoM is the chaperon to the
bioactive sphingolipid, sphingosine-1-phosphate (S1P). Several studies have since
contributed to expand the knowledge on apoM, S1P, and the apoM/S1P-complex in
cardiovascular diseases. For instance, the HDL-bound apoM/S1P complex serves as a
bridge between HDL and endothelial cells, maintaining a healthy endothelial barrier …
associated with high-density lipoprotein (HDL). It was found that apoM is the chaperon to the
bioactive sphingolipid, sphingosine-1-phosphate (S1P). Several studies have since
contributed to expand the knowledge on apoM, S1P, and the apoM/S1P-complex in
cardiovascular diseases. For instance, the HDL-bound apoM/S1P complex serves as a
bridge between HDL and endothelial cells, maintaining a healthy endothelial barrier …
