[HTML][HTML] Interferon gamma ELISPOT testing as a risk-stratifying biomarker for kidney transplant injury: results from the CTOT-01 multicenter study

DE Hricik, J Augustine, P Nickerson, RN Formica… - American Journal of …, 2015 - Elsevier
Previous studies suggest that quantifying donor-reactive memory T cells prior to kidney
transplantation by interferon gamma enzyme-linked immunosorbent spot assay
(IFNγELISPOT) can assist in assessing risk of posttransplant allograft injury. Herein, we
report an analysis of IFNγELISPOT results from the multicenter, Clinical Trials in Organ
Transplantation-01 observational study of primary kidney transplant recipients treated with
heterogeneous immunosuppression. Within the subset of 176 subjects with available …