[PDF][PDF] Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma
TM Habermann, EA Weller, VA Morrison… - Journal of clinical …, 2006 - Citeseer
TM Habermann, EA Weller, VA Morrison, RD Gascoyne, PA Cassileth, JB Cohn, SR Dakhil…
Journal of clinical oncology, 2006•CiteseerPurpose To address early and late treatment failures in older patients with diffuse large B-
cell lymphoma (DLBCL), we designed a two-stage randomized trial of cyclophosphamide,
doxorubicin, vincristine, and prednisone (CHOP) versus rituximab plus CHOP (R-CHOP),
with a second random assignment to maintenance rituximab (MR) or observation in
responding patients.
cell lymphoma (DLBCL), we designed a two-stage randomized trial of cyclophosphamide,
doxorubicin, vincristine, and prednisone (CHOP) versus rituximab plus CHOP (R-CHOP),
with a second random assignment to maintenance rituximab (MR) or observation in
responding patients.
Purpose
To address early and late treatment failures in older patients with diffuse large B-cell lymphoma (DLBCL), we designed a two-stage randomized trial of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) versus rituximab plus CHOP (R-CHOP), with a second random assignment to maintenance rituximab (MR) or observation in responding patients.
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