All preclinical trials should be registered in advance in an online registry.

PA Doevendans, S Chamuleau - European journal of …, 2014 - search.ebscohost.com
PA Doevendans, S Chamuleau
European journal of clinical investigation, 2014search.ebscohost.com
The article reports on the necessity of registering the pre-clinical and clinical trials in a
publicly accessible database before recruitment. Topics discussed include increasing cases
of the publication bias in clinical and pre-clinical studies, involvement of authors, journal
editors and research sponsors in creating the publication bias and need of proper approval
for the animal research. Erroneous interpretation of results may be caused by this
publication bias is also mentioned.
Abstract
The article reports on the necessity of registering the pre-clinical and clinical trials in a publicly accessible database before recruitment. Topics discussed include increasing cases of the publication bias in clinical and pre-clinical studies, involvement of authors, journal editors and research sponsors in creating the publication bias and need of proper approval for the animal research. Erroneous interpretation of results may be caused by this publication bias is also mentioned.
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