Functional and clinical relevance of chondroitin sulfate proteoglycan 4

M Campoli, S Ferrone, X Wang - Advances in cancer research, 2010 - Elsevier
The lack of effective conventional therapies for the treatment of advanced stage melanoma
has stimulated interest in the development of novel strategies for the management of
patients with malignant melanoma. Among them, immunotherapy has attracted much
attention because of the potential role played by immunological events in the clinical course
of melanoma. For many years, T cell-based immunotherapy has been emphasized in part
because of the disappointing results of the monoclonal antibody (mAb)-based clinical trials …