Structure of serum response factor core bound to DNA
L Pellegrini, S Tan, TJ Richmond - Nature, 1995 - nature.com
L Pellegrini, S Tan, TJ Richmond
Nature, 1995•nature.comThe human serum response factor is a transcription factor belonging to the MADS domain
protein family with members characterized from the plant and animal kingdoms. The X-ray
crystal structure of the serum response factor core in a specific-recognition DNA complex
shows that the functions of DNA binding, dimerization and accessory-factor interaction are
compactly integrated into a novel protein unit. The intrinsic and induced conformation of the
serum response element DNA is the principal DNA feature recognized in the specific …
protein family with members characterized from the plant and animal kingdoms. The X-ray
crystal structure of the serum response factor core in a specific-recognition DNA complex
shows that the functions of DNA binding, dimerization and accessory-factor interaction are
compactly integrated into a novel protein unit. The intrinsic and induced conformation of the
serum response element DNA is the principal DNA feature recognized in the specific …
Abstract
The human serum response factor is a transcription factor belonging to the MADS domain protein family with members characterized from the plant and animal kingdoms. The X-ray crystal structure of the serum response factor core in a specific-recognition DNA complex shows that the functions of DNA binding, dimerization and accessory-factor interaction are compactly integrated into a novel protein unit. The intrinsic and induced conformation of the serum response element DNA is the principal DNA feature recognized in the specific complex.
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