Post-transplant obliterative bronchiolitis and other late lung sequelae in human heart-lung transplantation
CM Burke, J Theodore, KD Dawkins, SA Yousem… - Chest, 1984 - Elsevier
Since March 1981, 19 patients have undergone heart-lung transplantation for end-stage
pulmonary vascular disease, with 14 long-term survivors. In five of the survivors, obstructive
airway disease has developed with the superimposition of a progressive restrictive
ventilatory defect in three of them. None of these five patients showed a tendency for
spontaneous improvement of flow rates. Biopsy and postmortem material was available in
four of the five patients and showed obliterative bronchiolitis (OB) in three. A fourth patient …
pulmonary vascular disease, with 14 long-term survivors. In five of the survivors, obstructive
airway disease has developed with the superimposition of a progressive restrictive
ventilatory defect in three of them. None of these five patients showed a tendency for
spontaneous improvement of flow rates. Biopsy and postmortem material was available in
four of the five patients and showed obliterative bronchiolitis (OB) in three. A fourth patient …
